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One or more keywords matched the following properties of Landay, Alan
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overview Other Appointments: The Thomas J. Coogan, Sr., MD, Chair of Immunology, Rush Medical College. Alan L. Landay, PhD, is the professor of the Department of Immunity & Emerging Pathogens and principal investigator of the Rush Immunology Specialty Laboratory, or ISL, with 35 years experience in studies of HIV immunopathogenesis. He has worked with the AIDS Clinical Trials Group since its beginning and has directed the ISL since it began. His studies on immunophenotyping and innate immunity in HIV disease have made significant contributions to this field. These early studies were carried out in a newly recognized population of hemophiliacs that were shown to develop AIDS. This work was extended with more recent publications using multi-parameter flow cytometry to define monocyte subsets and the critical role of monocytes and innate immune cell activation in HIV pathogenesis. These papers have contributed to a shift in thinking about HIV as an adaptive immune disease to one focused on innate cell driven inflammation linked to the development of immunosenescence. My Scopus ID is 14325119400. My NIH COMMONS name is ALANDAY. Research Areas: HIV/AIDS, aging. My Faculty Profile at Rush University Medical Center: https://www.rushu.rush.edu/faculty/alan-l-landay-phd My Laboratory: https://www.rushu.rush.edu/research/departmental-research/microbial-pathogens-and-immunity-research/laboratory-alan-landay-phd My NCBI Bibliography: https://www.ncbi.nlm.nih.gov/pubmed/?term=Landay+A My Scopus: https://www.scopus.com/authid/detail.uri?authorId=14325119400 Education: PhD, University of Pittsburgh Medical School BS, Penn State University
One or more keywords matched the following items that are connected to Landay, Alan
Item TypeName
Concept Immunity, Innate
Academic Article Relationship between target cell cycle and susceptibility to natural killer lysis.
Academic Article Characterization of quantitative and functional innate immune parameters in HIV-1-infected Colombian children receiving stable highly active antiretroviral therapy.
Academic Article The role of bacterial vaginosis and trichomonas in HIV transmission across the female genital tract.
Academic Article Innate immunity and chronic immune activation in HCV/HIV-1 co-infection.
Academic Article Vaccines and immunology. Recent advances in HIV/AIDS vaccine development.
Academic Article Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms.
Academic Article Biology of mucosally transmitted sexual infection-translating the basic science into novel HIV intervention: a workshop summary.
Academic Article HIV infection and aging of the innate immune system.
Academic Article Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women.
Academic Article Characterization of IL-22 and IL-17 Expressing Leukocytes in the Cervix.
Academic Article Innate immune defenses in HIV-1 infection: prospects for a novel immune therapy.
Academic Article The effects of commensal bacteria on innate immune responses in the female genital tract.
Academic Article Cervicovaginal levels of lactoferrin, secretory leukocyte protease inhibitor, and RANTES and the effects of coexisting vaginoses in human immunodeficiency virus (HIV)-seronegative women with a high risk of heterosexual acquisition of HIV infection.
Academic Article Antibody-dependent cell-mediated cytotoxicity in cervical lavage fluids of human immunodeficiency virus type 1--infected women.
Academic Article Early and delayed benefits of HIV-1 suppression: timeline of recovery of innate immunity effector cells.
Academic Article Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.
Academic Article Associations of Innate and Adaptive Immune Cell Subsets With Incident Type 2 Diabetes Risk: The MESA Study.
Academic Article Innate and adaptive immune cell subsets as risk factors for coronary heart disease in two population-based cohorts.
Academic Article Natural killer cells, gamma delta T cells and classical monocytes are associated with systolic blood pressure in the multi-ethnic study of atherosclerosis (MESA).
Academic Article COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions.
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  • Immunity Innate